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Cell Membrane Integrity Kit consists of a spectrally distinct proprietary dye that is taken up by cells with compromised membranes and excluded by healthy cells with intact membranes. This kit can be multiplexed with other Intellicyt reagents.
The Cell Membrane Integrity dyes are fluorescent molecules that are cell impermeant. Healthy cells with intact cell membranes will exclude the dyes. Unhealthy cells with compromised membranes will allow entry of the dye into the intracellular space. Upon entry to the cell, the dye localizes to the nucleus and binds to DNA by intercalation.
Figure 1. Dead and/or dying cells with compromised cell membranes will stain brightly with Cell Membrane Integrity Dye (V/Blue). Live cells with intact cell membranes will remain unstained (VL1-H low).
|Dimensions||15 × 13 × 8 in|
5 x 384, 20 x 384, 50 x 384